Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as molindone have an increased chance of death during treatment.
Molindone is not approved by the Food and Drug Administration (FDA) for the treatment of behavior problems in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking molindone. For more information visit the FDA website: Web Site
Molindone is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Molindone is in a class of medications called conventional (typical) antipsychotics. It works by decreasing abnormal excitement in the brain.
Molindone comes as a tablet to take by mouth. It is usually taken three or four times a day. Try to take molindone at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take molindone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor will probably start you on a low dose of molindone and gradually increase your dose after 3 to 4 days. Later, your doctor may increase or decrease your dose, depending on your response to the medication and the side effects you experience. Be sure to tell your doctor how you are feeling during your treatment with molindone.
Molindone may help to control your condition but will not cure it. Continue to take molindone even if you feel well. Do not stop taking molindone without talking to your doctor. It may take several weeks or longer for you to feel the full benefit of molindone.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before taking molindone, tell your doctor and pharmacist if you are allergic to molindone, any other medications, or any of the ingredients in molindone. Ask your pharmacist for a list of the ingredients.tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants; barbiturates such as pentobarbital (Nembutal), phenobarbital, and secobarbital (Seconal); medications for anxiety, mental illness, or seizures; narcotic (opiate) medications for pain; phenytoin (Dilantin, Phenytek); sedatives; sleeping pills; tetracycline antibiotics such as demeclocycline, doxycycline (Doryx, Doxteric, Vibramycin, others), minocycline (Dynacin, Minocin, Solodyn), and tetracycline (Achromycin V, in Pylera); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.tell your doctor if you have or have ever had depression, breast cancer, or a low number of white blood cells in your blood.tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breastfeeding. If you become pregnant while taking molindone, call your doctor. Molindone may cause problems in newborns following delivery if it is taken during the last months of pregnancy.if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking molindone.you should know that this medication may make you drowsy and may affect your thinking and movements. Do not drive a car or operate machinery until you know how this medication affects you.ask your doctor about the safe use of alcohol while you are taking molindone. Alcohol can make the side effects of molindone worse.
Unless your doctor tells you otherwise, continue your normal diet.
Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose, and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Molindone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: drowsinessdry mouthblurred visionincreased salivanauseaconstipationdifficulty urinatingblank facial expressionshuffling walkunusual, slowed, or uncontrollable movements of any part of the bodyrestlessnessexcitement or increased activitydepressioninappropriate happinessbreast enlargementbreast milk productionmenstrual period changes (missed periods or heavy bleeding)changes in sex drive
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment,: fevermuscle stiffnessconfusionfast or irregular heartbeatrashsweatingneck crampstongue that sticks out of the mouthtightness in the throatdifficulty breathing or swallowingfine, worm-like tongue movementsuncontrollable, rhythmic face, mouth, or jaw movementsseizureschanges in vision
Molindone may cause other side effects. Tell your doctor if you have any unusual problems while you are taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( Web Site) for more information if you do not have access to a take-back program.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include the following: unusual, slowed, or uncontrollable movements of any part of the bodyloss of consciousness
Keep all appointments with your doctor. Your doctor may order certain lab tests to check your body's response to molindone.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
¶This branded product is no longer on the market. Generic alternatives may be available.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: January 15, 2016.