Reiter’s syndrome is an inflammatory reaction to an infection somewhere in the body. It usually follows an infection of the urinary, genital, or digestive tract. It is treated with rest and medication.
Reiter's syndrome is triggered by certain infections. It is usually caused by the bacterium
. Chlamydia is transmitted through sexual contact with an infected partner. The infection can also begin in the digestive system. In these cases, the infection occurs after eating food tainted with bacteria.
Factors that may increase your chance of getting Reiter's syndrome include: Family members with Reiter's syndromeInheriting the genetic trait associated with Reiter’s syndrome (HLA-B27)Having a chlamydia infection or an infection in the digestive system
Symptoms occur in the joints, the eyes, the urinary tract, and genitals. Men and women may experience different symptoms. In rare cases, heart problems may develop later in the disease.
Swelling, pain, and redness, especially in the knees, ankles, and feetHeel painBack pain and stiffness
In men: Burning sensation when passing urinePenile discharge
Male Urinary System
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In women: Burning sensation when passing urineInflamed vagina and cervix
Rash, especially on the palms or solesUlcers in the mouth or on the tongueWeight lossPoor appetiteFatigueFever
Your doctor will ask about your symptoms and medical history. A physical exam will be done. Your doctor uses these findings to help make the diagnosis. There is no specific test to check for Reiter’s syndrome.
Your doctor may need to test your bodily fluids and tissues. This can be done with: Blood testsCulture, gram stain, or other testsRemoval of fluid from the affected joints
Your doctor may need pictures of your bodily structures. This can be done with
There is no cure for Reiter’s syndrome. Most people recover from the initial episode within 12 months. Others develop mild, chronic arthritis. Some suffer from additional episodes of the disorder.
Treatment aims to relieve symptoms and may include:
Short-term rest to take the strain off the joints.
This includes: Assistive devices as recommended by your doctorOccupational therapy to learn how to take it easy on joints during daily activities
Your doctor may prescribe some of the following: Nonsteroidal anti-inflammatory drugs (NSAIDs)SulfasalazineSteroid injections into the inflamed jointTopical steroid creams applied to skin lesionsAntibiotics to treat the triggering infectionMedication that suppresses the immune systemEye drops
To reduce your chance of Reiter's syndrome:
Always use a
during sexual activity
Have a monogamous relationshipDo not go back and forth between sexual partners
Have regular checkups for
sexually transmitted diseasesWash hands before eating or handling foodOnly eat foods that have been stored and prepared properly
Questions and answers about reactive arthritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at:
http://www.niams.nih.gov/health_info/reactive_arthritis/default.asp. Updated October 2012. Accessed May 21, 2013.
Reactive arthritis. American College of Rheumatology website. Available at:
http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/reactivearthritis.asp. Updated February 2013. Accessed May 21, 2013.
Last reviewed November 2015 by Warren A. Bodine, DO, CAQSM
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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