Skin cancer is when cancer cells grow in the skin.
The two most common kinds of skin cancer are: Basal cell carcinoma
—Basal cell carcinoma is the most common form of skin cancer. This cancer usually grows slowly and rarely spreads to other tissues in the body.
Basal cell carcinoma is rarely fatal but it can cause damage to the nearby tissue. If there is risk of damage, the cancer may need treatment or removal.Squamous cell carcinoma
—Squamous cell carcinoma is the second most common form of skin cancer.
The cancer develops in the uppermost layer of skin cells. Squamous cell carcinoma usually grows slowly. It is rarely fatal if treated early. However, the cancer can be lethal if it spreads beyond the skin.
Basal Cell Carcinoma
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It is important that skin cancers be found and treated early. If left untreated, they can quickly invade and destroy nearby tissue.
Cancer occurs when skin cells in the body divide without control or order. When cells keep dividing uncontrollably when new cells are not needed, a mass of tissue forms. This is called a growth or tumor. Unlike benign tumors, malignant tumors can invade nearby tissues and spread to other parts of the body.
Basal and squamous cell cancers are more common in men and in people over 50 years old. These cancers are most likely to occur in people with: Fair skin that freckles easilyRed or blonde hairLight-colored eyesCaucasian skin
Other factors that increase your risk of skin cancer include: Personal history of skin cancerExposure to ultraviolet radiation from the sun or artificial radiation from a tanning bedExcessive sun exposure without protective clothing or sunscreenSkin damage from burns or infectionsExposure to arsenic, industrial tar, coal, paraffin, and certain types of oilRadiation
Light treatments for
, especially psoralen ultraviolet A (PUVA)
Having a weak immune system due to illness or medicationsCertain genetic diseases, such as basal cell nevus syndrome or xeroderma pigmentosum
Most skin cancers do not cause symptoms. The most common first symptom of skin cancer is a change in the skin.
Basal cell carcinoma may appear as a: Slowly expanding, painless growthBleeding scab or sore that heals and recursFlat, firm, pale areaSmall, raised, pink, red, shy, or pearly areas thay may bleed easilyLarge oozing, crusted area
Squamous cell carcinoma may appear as a: Growing lumps with rough, scaly, or crusted surfacesSlow-growing flat, reddish patches in the skinRecurrent, nonhealing ulceration or bleeding
Skin cancers can occur anywhere, but are more common on places that are exposed to the sun.
You will be asked about your symptoms and medical history. A physical exam will be done.
You may have a
. The sample can then be examined for cancer cells.
In cases where the growth is large, or has been present for a long time, the lymph nodes in the area will be checked. More tests may be advised to determine if the cancer has spread to other parts of the body.
Talk to your doctor about the best treatment for you. Treatment may include one or more of the following:
Many skin cancers can be cut from the skin quickly and easily.
In fact, the cancer is sometimes completely removed during biopsy and no further treatment is needed. Surgical techniques include:
This involves scooping the cancer out with a curette, an instrument with a sharp, spoon-shaped end. The area is treated with an electric current to control bleeding. This also kills any cancer cells remaining around the edge of the wound.
This technique is used for small or superficial cancers.
Mohs surgery is the removal of all of the cancerous tissue. The surgeon will try to remove as little healthy tissue as possible. This method is used to remove: Large tumorsTumors in hard-to-treat placesTumors of undetermined shape and depthCancers that have recurred
The procedure is done by specially trained dermatologic Mohs surgeons. The cancer is shaved off one thin layer at a time. Each layer is checked under a microscope for cancer cells until the entire tumor is removed.
Liquid nitrogen is used to freeze and kill the abnormal cells. After the area thaws, the dead tissue falls off. More than one freezing may be needed to remove the growth completely. This method may be used to treat precancerous skin conditions (actinic keratoses) and certain small or superficial skin cancers.
Laser therapy uses a narrow beam of light to remove or destroy cancer cells. This method is sometimes used for cancers in the outer layer of skin.
Radiation therapy uses radiation to kill cancer cells and shrink tumors.
Topical chemotherapy is the use of drugs to kill cancer cells. The drugs can be creams or lotions. This method is successful in treating precancerous conditions and cancers limited to the outer layer of the skin. The most common topical chemotherapy used is a form of 5-fluorouracil (5-FU) .
Medications such as imiquimod increase your body's own reponse to fight the cancer cells.
To prevent skin cancer: Avoid spending too much time in the sun.Avoid exposing your skin to the sun between 10:00 AM and 2:00 PM standard time, or 11:00 AM to 3:00 PM daylight saving time.Protect your skin from the sun with clothing. Wear a shirt, sunglasses, and a hat with a broad brim.Use broad-spectrum (UVA and UVB) sunscreens with a sun protection factor (SPF) of 30 or more on skin that will be exposed to the sun.Use a protective lip balm. Wear sunglasses with 99% or 100% UV absorption to protect your eyes.Don't use sun lamps or tanning booths.
Take the following precautions to find skin cancer early: If you have any of the symptoms listed above, have your skin examined by a doctor.If you have fair skin, have your skin checked by a doctor.Learn how to do a skin self-exam
Alberta Provincial Cutaneous Tumour Team. Prevention of skin cancer. Edmonton (Alberta): CancerControl Alberta; 2013 Feb. 27 p. (Clinical practice guideline; no. CU-014). Available at: http://www.guideline.gov/content.aspx?id=48130#Section420. Accessed February 25, 2015.
Basal cell carcinoma of the skin. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated December 18, 2014. Accessed February 25, 2015.
Skin cancer: basal and squamous cell. American Cancer Society website. Available at:
http://www.cancer.org/acs/groups/cid/documents/webcontent/003139-pdf.pdf. Updated February 20, 2014. Accessed February 25, 2015.
Skin cancer. National Cancer Institute website. Available at:
http://www.cancer.gov/cancertopics/types/skin. Accessed February 25, 2015.
Squamous cell carcinoma. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated January 16, 2015. Accessed February 25, 2015.
Sunscreen FAQs. American Academy of Dermatology website. Available at: https://www.aad.org/media-resources/stats-and-facts/prevention-and-care/sunscreens. Accessed February 25, 2015.
Last reviewed February 2015 by Mohei Abouzied, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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