Anything that causes irritation, inflammation, fluid retention, or an abnormal growth in or around the carpal tunnel can cause carpal tunnel syndrome, including:

    
  • Repetitive movements of the hands, wrists, or fingers—especially overactive use of a computer keyboard, certain musical instruments, or hand tools
  • Use of vibrating equipment or tools
  • A narrow carpal tunnel (due to heredity or other causes)
  • Wrist injury:     
  • Burns
  • Broken bones
  • Compression or crush injuries
  • Arthritis leading to swelling within the carpal tunnel
  • Diabetes
  • Raynaud's disease , which impairs blood flow in the hands
  • Water retention due to:     
  • Kidney disease
  • Amyloidosis
  • Heart disease
  • Hormone-related conditions, such as:     
  • Pregnancy
  • Breastfeeding
  • Menopause
  • Hypothyroidism
  • Cushing's disease
  • Excess growth hormone
  • Medications, such as:     
  • Birth control pills
  • Cortisone pills or shots
  • Some high blood pressure drugs
  • Tumors and cysts in the carpal tunnel