Desloratadine is approved for the treatment of perennial
and long term
in people aged 6 months and older. For those who suffer from seasonal allergic rhinitis (SAR), the medication can be used at age 2 years and up.
SAR (or hay fever) occurs during specific times of the year when allergens (things you are allergic to) are in the air. Seasonal allergies are usually at their peak during spring or fall. Perennial allergic rhinitis is related to allergies present year-round, such as cat, dog, or dustmite.
When you breathe in an allergen, cells in your nasal passages release a chemical called histamine. Histamine causes your nose to feel itchy and increases swelling and mucus production in the nasal passages.
The following are symptoms of allergic rhinitis: SneezingItching in the nose, eyes, throat, and earsRed, watery eyesRunny nose, nasal congestionSinus pressure
Postnasal drip and
coughHeadacheDark circles under your eyes
Desloratadine is taken once per day. It is a non-sedating antihistamine, which means it blocks the action of the released histamine with less risk of making you feel drowsy.
Some of the most common side effects experienced by those taking desloratadine are: Sore throatDry mouthSleepinessFatigueSore muscles
Desloratadine is not for everyone. Safety in children younger than 6 months has not been established. In addition, there have been no adequate and well-controlled studies in pregnant women, and desloratadine passes into breast milk. So, if you are pregnant or nursing, talk with your doctor about possible alternative options for treating SAR.
If you cannot take desloratadine, you do have options for relief.
Other antihistamines or teatments may help you manage your allergies. Options include: Other oral antihistamines (eg, fexofenadine, cetirizine)Intranasal steroid sprays (eg, fluticasone, triamcinolone)Intranasal antihistamines sprays (eg, azelastine, olopatadine)
Immunotherapy, such as sublingual liquid or pills
Talk to your doctor about the alternatives and what may work best for you.
Allergic rhinitis. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated July 14, 2014. Accessed December 11, 2014.
Desloratadine. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated January 18, 2013. Accessed December 14, 2014.
Desloratadine. United States National Library of Medicine from National Institutes of Health website. Available at:
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a602002.html. Updated October 1, 2010. Accessed December 14, 2014.
Last reviewed December 2014 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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