Polymyalgia rheumatica (PMR) is an inflammatory disorder. It results in muscle pain and stiffness in the body. The effects are most common in the shoulders, arms, hips, and thighs. About 15% of people with PMR will also develop
giant cell arteritis
GCA is an inflammation of the lining of the arteries, the blood vessels that carry blood away from the heart.
Giant Cell Arteritis
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The exact cause is not known. Inflammatory conditions may be due to some problem with the immune system. Some evidence suggests that certain viruses could be responsible for PMR. Genetic factors may also play a role.
PMR is most common in Caucasian women, aged 65 years and older.
Symptoms may include: Muscle pain and/or stiffness in the hip, shoulder, or neck areasStiffness in the morningFeverUnexplained weight lossFatigueMood changes
Your doctor will ask about your symptoms and medical history. A physical exam will be done. There is no single test for PMR. To support the diagnosis and rule out other conditions, tests may include: Erythrocyte sedimentation rate (ESR), a blood test that measures how quickly red blood cells fall to the bottom of a test tube.Rheumatoid factor (RF), a blood test that looks for RF antibodies in the blood.Complete blood count, a blood test that measures the amount of different blood cells present in whole blood.C-reactive protein, a protein that is elevated in the blood when inflammation is present.
Imaging studies take pictures of internal body structures. These may include
If you have PMR, your doctor may also consider the possibility of GCA. Evaluation for GCA includes: Physical exam, including vision testBiopsy
of an affected blood vessel is necessary to confirm the diagnosis
Symptoms of PMR will disappear without treatment within several months to years. Treatment leads to dramatic improvement, which may occur within 24-48 hours.
Treatment may include: Anti-inflammatory medicationsCorticosteroids
Supplements, such as
vitamin DPhysical therapy to help with strength, flexibility, and mobility
There are current guidelines to prevent PMR.
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Last reviewed June 2013 by Michael J. Fucci, DO; Brian Randall, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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