Many authorities advise more aggressive treatment of
high triglycerides. Here is a rundown on these blood fats and why improving them is important for your health.
Triglycerides are the chemical form most fats take in the body. They have a backbone consisting of a glycerol molecule to which three fatty acid molecules are attached. All glycerol molecules are the same, but the fatty acids may vary greatly. The types of fatty acids that are attached to the triglyceride determine whether it is a saturated, trans, monounsaturated, or polyunsaturated fat. These triglycerides come from fats in the foods you eat or they are made from other energy sources, like carbohydrates. When you eat a meal, the calories your body isn't using right away are converted into triglycerides and stored in your body's fat cells. When your body needs energy between meals, triglycerides are released from fat tissue to be used for making energy.
Having too much triglyceride in your blood can adversely affect your health in several ways. Extremely high triglyceride levels can trigger an attack of
pancreatitis. Pancreatitis is the inflammation of the pancreas, an abdominal organ that secretes digestive enzymes.
Research has also identified high triglycerides as an important risk factor for cardiovascular diseases such as
hardening of the arteries. Though the data are not as well established as for
high cholesterol, it's a huge issue since
coronary heart disease
causes nearly 600,000 deaths each year and is the leading cause of death in the US.
After you have gotten the results from a fasting blood fat profile, you can compare your triglyceride score with what experts have to say about these values:
|less than 150||Normal|
and greater||Very high|
If your triglyceride level is not normal, you and your doctor may want to search for a treatable cause. Factors that can increase your risk of high triglycerides include:
Sex—Men are more susceptible than women. After
menopause, a woman's risk increases.
Age—The risk of high triglycerides increases with age.
Genetic disorders, including a family history of high triglycerides or
Lifestyle factors such as:
obesityHigh carbohydrate intake
Medical disorders, such as:
or thyroid disease
or high blood levels of uric acid
or insulin resistance syndrome—excess abdominal fat, high blood pressure, and elevated blood levels of fat and sugarHepatitis
Certain drugs such as:
Immunosuppressive medicationsEstrogenRetinoidsBeta-blockers and diuretics
Treatment for abnormal triglyceride levels usually involves lifestyle changes. Saturated fat should make up less than 7% of the calories you consume.
Most saturated fat should be replaced with healthful monounsaturated and polyunsaturated fats. Increasing your intake of
omega-3 fatty acids
is especially important. Omega-3 fatty acids are polyunsaturated fats found in fatty fish (such as salmon, mackerel, herring, sardines, trout, and tuna) and certain plant sources, including flax seeds, canola oil, and walnut oil.
The American Heart Association recommends eating fish at least twice each week. Taking fish oil capsules can also help lower triglyceride levels.
Weight loss also helps lower your triglyceride levels, as can limiting alcohol intake, quitting smoking, and getting regular, moderate exercise. If you are already at risk for heart disease, talk with your doctor before starting an exercise program.
When lifestyle measures fail to control triglyceride levels, your doctor may advise lowering your triglycerides with the help of medication. Drug treatment may also be advised if you have diabetes or another chronic disease associated with coronary artery disease.
In addition to fish oil capsules, medications such as nicotinic acid, fibrates, or statins can be used to help optimize your triglycerides.
American Dietetic Association. Disorders of lipid metabolism evidence-based nutrition practice guideline. National Guideline Clearinghouse website. Available at:
http://www.guideline.gov/content.aspx?id=32479&search=disorders+of+lipid+metabolism. Published March 2011. Accessed July 16, 2014.
Cardiovascular risk prediction. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated May 2, 2014. Accessed July 16, 2014
Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. Washington, DC: National Academies Press; 2002. National Academies Press website. Available at:
http://www.nap.edu/openbook.php?isbn=0309085373. Accessed July 16, 2014.
Essential fatty acids. Oregon State University. Linus Pauling Institute website. Available at:
http://lpi.oregonstate.edu/infocenter/othernuts/omega3fa/. Updated April 2014. Accessed July 16, 2014.
Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III).
Fish and omega-3 fatty acids. American Heart Association website. Available at:
http://www.heart.org/HEARTORG/GettingHealthy/NutritionCenter/HealthyDietGoals/Fish-and-Omega-3-Fatty-Acids_UCM_303248_Article.jsp. Updated May 14, 2014. Accessed July 16, 2014.
Hypertriglyceridemia. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated May 29, 2014. Accessed July 16, 2014.
Lauer MS, Fontanarosa PB. Updated guidelines for cholesterol management (editorial).
Leading causes of death. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/nchs/fastats/lcod.htm. Updated January 27, 2012. Accessed July 16, 2014.
Low HDL (high-density lipoprotein) cholesterol level. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed/. Updated January 9, 2013. Accessed July 16, 2014.
NCEP ATP III guidelines.
EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated November 14, 2013. Accessed July 15, 2014.
Oh RC, Lanier JB. Management of hypertriglyceridemia.
Am Fam Physician.
American Academy of Family Physicians website. Available at: http://www.aafp.org/afp/2007/0501/p1365.html. Accessed July 15, 2014.
Safeer RS, Ugalat PS. Cholesterol treatment guidelines update. Am Fam Physician. 2002;65(5):871-881. American Academy of Family Physicians website. Available at:
http://www.aafp.org/afp/20020301/871.html. Accessed July 15, 2014.
Triglycerides. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Encyclopedia/Heart-Encyclopedia_UCM_445084_Encyclopedia.jsp?levelSelected=20&title=triglycerides. Accessed July 15, 2014.
Last reviewed July 2014 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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