People with metabolic syndrome are at increased risk of: Heart diseaseStrokeType 2 diabetes
Metabolic syndrome is believed to be due to a combination of: Genetic factors, which you inherit from your familyEnvironmental factors such as diet and physical activity level
The more risk factors you have for metabolic syndrome, the greater your likelihood of developing it. The risk of having metabolic syndrome also increases with age. If you have a number of risk factors, ask your doctor what you can do to reduce your risk.
Examples of these risk factors include: Ethnicity—Mexican American women, Caucasians, and African Americans have a higher risk.Obesity—You are more likely to develop many of the underlying conditions of metabolic syndrome if you are overweight, especially if that extra weight is around your waist or if your obesity began at a young age.
Having disorders or conditions associated with metabolic disorder such as:
Type 2 or
High blood pressureCholesterol problemsCoronary artery disease
—a heart condition where the arteries that supply blood to the heart narrow, increasing the chances of a heart attack
Polycystic ovary syndrome
—a hormonal disorder that occurs when a woman produces an excess of male hormones
Genes—Having a family history of the disorders listed abovePhysical inactivity
Poor diet—Eating a diet high in calories, sugar, saturated fats, and starchy foodsand low in dietary
increases your risk.
Unhealthy habits, such as
smokingCertain medication, such as atypical antipsychotics
Deen D. Metabolic Syndrome: time for action.
Am Fam Physician
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the Third National Health and Nutrition Examination Survey.
Gami AS, Witt BJ, Howard DE, et al. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies.
J Am Coll Cardiol.
Grundy SM. Metabolic syndrome: a multiplex cardiovascular risk factor.
J Clin Endocrinol Metab
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome.
Weiss R. Dziura J, Burgert TS, et al. Obesity and the metabolic syndrome in children and adolescents.
N Engl J Med
1/2/2014 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed: Koyama S, Ichikawa G, et al. Adiposity rebound and the development of metabolic syndrome. Pediatrics. 2013 Dec 23.
1/22/2015 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed: Xu Y, Shen S, et al. Metabolic syndrome risk after gestational diabetes: Asystematic review and meta-analysis. PLoS One. 2014;9(1):e87863.
Last reviewed May 2015 by Kim A. Carmichael, MD, FACP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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