Calcium is a mineral needed for bone health, muscle movement, and nerve function. Hypocalcemia is lower than normal levels of calcium in your blood.
Vitamin D helps to absorb calcium from food or supplements. Once in your body, calcium may be stored in the bones or exist in the blood. It may also be excreted through the kidneys. Levels of calcium in the blood are normally regulated by hormones from the parathyroid gland. Hypocalcemia may occur if an illness or medication interferes with this process. The most common cause of hypocalcemia is kidney failure.
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Factors that may interfere with hormones and can lead to hypocalcemia include: Parathyroid problemsPrevious thyroid surgeryAutoimmune diseaseCertain types of brain cancerGenetic disorders
Factors that may decrease your intake of calcium include: Lack of vitamin D in the diet or through sunlight exposureLack of magnesium in the dietDigestive problems such as inflammatory bowel diseaseCertain medications such as diuretics or laxatives
Other factors that may increase your risk of hypocalcemia include: Inflammation of the pancreasKidney disease or failure—too much calcium excretedCertain medications such as bisphosphonates—move calcium to the bones
Early hypocalcemia may not have any symptoms. When symptoms do occur, they may include: FatigueMuscle spasms Tingling and numbnessIrregular heartbeatSkin changes such as dry, scaly skinCoarse hair that easily breaksDifficulty breathing in newborns
You will be asked about your symptoms and medical history. A physical exam will be done.
Your bodily fluids may be tested. This can be done with: Blood tests, possibly including genetic testingUrine tests
Images may be taken of your bodily structures. This can be done with X-rays.
The electrical activity of your heart may be tested. This can be done with an electrocardiogram (ECG).
Talk with your doctor about the best treatment plan for you. Options include:
You may be given supplements through an IV or pills. Supplements may include: CalciumVitamin DMagnesium—if this is low as well
Medications may also be given to control the condition causing the problem or to increase the amount of calcium in the blood. Medication options may include: Thiazide diuretics to decrease the amount of calcium lost through urinationParathyroid hormone to treat chronic hypoparathyroidism
Your current medications may be changed if they are the cause of your hypocalcemia.
Your doctor may advise you to increase your intake of calcium and vitamin D. You may be referred to a dietitian.
To help reduce your chance of getting hypocalcemia, take these steps: Eat a diet that contains enough calcium and vitamin D. This is especially important during pregnancy. Take calcium or vitamin D supplements if advised by your doctor. Manage conditions such as chronic kidney disease and hypoparathyroidism.
Cooper M, Gittoes N. Diagnosis and management of hypocalcaemia. BMJ. 2008 June 7;336(7656):1298-1302.
Hypocalcemia. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated June 2, 2014. Accessed February 17, 2015.
Hypocalcaemia. Patient UK website. Available at: http://www.patient.co.uk/doctor/Hypocalcaemia.htm. Updated December 14, 2011. Accessed February 17, 2015.
Last reviewed February 2015 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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