Chronic traumatic encephalopathy (CTE) is a deterioration of the brain. It is caused by the buildup of a protein called tau. The brain damage caused by CTE can lead to severe mental and physical disabilities. The condition gets worse over time.
Researchers have a found a link between repetitive head injuries and CTE. The head injury may involve: A blow or jolt to the headSevere jarring or shakingAbruptly coming to a stop
Over time, these injuries can lead to abnormal groups of tau proteins. These proteins can create tangled masses in the brain. The tangles can block normal brain function. Similar tangles are seen in people with Alzheimer’s disease.
Having a history of head injuries puts you at risk for CTE later in life. People who may be at the highest risk include those who: Participate in contact sports, especially professional boxers, football players, hockey players, wrestlers, and soccer playersHave been in combat military serviceHave been physically abusedHave severe seizuresHave a developmental disability and engage in self-abusive behavior (head banging)
Symptoms include: Depression, including feeling suicidalParanoiaAggressionApathyIrritabilityAgitationImpulsivenessPoor concentrationMemory problemsConfusionPoor judgmentTremorMuscle twitching
The symptoms may develop many years after the head injuries.
Your doctor will: Ask about your symptoms.—It is important that you and your family members talk about any behavior or personality changes that you have had.Take your medical history.—Your doctor will focus on your history of head injuriesDo a physical exam.
To gain more information about your brain and to rule out other conditions, your doctor may order tests, such as:
CT scanMRI scan
PET scanBlood testsNeuropsychological tests
CT Scan of the Head
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At the present time, the only way to clearly diagnose CTE is for a doctor to examine the brain after a person has died. This is how researchers are learning more about CTE.
Treatment for CTE is an area that is being studied. Depending on your symptoms, though, your doctor may recommend: Taking certain medicines (eg, antidepressants, antipsychotics, mood stabilizers)Making lifestyle changes, such as exercising regularly, eating a healthy diet, and avoiding alcohol and drugsWorking with a therapist and joining a support group to help with the emotional challenges
You may be referred to a doctor who specializes in head injuries.
When playing sports, you can reduce your risk of CTE by: Following your doctor’s instructions after suffering a concussion—This includes waiting to return to sports until your doctor says it is safe to do so. Avoiding dangerous game playWearing proper protective equipment (such as helmets)
Other steps that you can take to reduce head injuries off the field include: Wear a helmet when doing any at-risk activity, like riding a motorcycle or bicycle, skiing, snowboarding.Wear a seatbelt in the car.Do not drink and drive or get into a vehicle with someone who is under the influence.Make your home safe (eg, remove items that you could easily trip over, install night lights).Get help right away if you are in an abusive relationship.
McKee A, Cantu R, Nowinski C, et al. Chronic traumatic encephalopathy in athletes: progressive tauopathy following repetitive head injury. J Neuropathol Exp Neurol. 2009; 68(7):709-735.
Last reviewed August 2013 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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