FRIDAY, July 1 (HealthDay News) -- Nausea and vomiting after
waking from general anesthesia may be hereditary, a new study
DNA samples from 122 patients with severe postoperative nausea
and vomiting (PONV) were analyzed by Penn State College of Medicine
researchers. They initially identified 41 genetic targets (single
nucleotide polymorphisms -- SNPs) that might be related to
Further analysis led them to at least one SNP that was common to
all the patients, according to the study in the July issue of the
"We hope identification of the SNP will help better predict
which patients are more susceptible to PONV and enable
anesthesiologists to take appropriate precautions before those
patients receive anesthesia," lead author Dr. Piotr K. Janicki said
in a news release from the American Society of
This is the first study to analyze the genetics of patients with
PONV and could lead to the development of a genetic test before
surgery to determine a patient's risk.
Previous research has identified a number of contributing
factors to PONV: being female; use of volatile anesthetics;
previous history of PONV or motion sickness; and use of intra- or
postoperative opioid drugs such as morphine or codeine.
The Canadian Anesthesiologists' Society has more about
common side effects after anesthesia.
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