You have probably heard that aspirin prevents
in people with
. But did you know that it also works in healthy people without pre-existing cardiovascular problems? Research has shown that aspirin is effective in preventing first heart attacks in healthy people who have risk factors for the disease. It does this by staving off blood clots that can trigger heart attacks. But does this mean everyone should be taking aspirin therapy? According to the studies, the answer to that question is no, unless you have risk factors for the disease.
The US Preventive Services Task Force (USPSTF), an independent panel of medical experts, recommends aspirin therapy in the following groups:
Men aged 45-79 to reduce the risk of heart attacks
Women aged 55-79 to reduce the risk of
The American Heart Association (AHA) recommends aspirin therapy for people who are considered to be at high risk of having a heart attack. A person is high risk if they have conditions such as established heart disease, peripheral arterial disease, abdominal aortic aneurysm, chronic renal disease, or diabetes. People may also be at high risk they have high blood pressure, high cholesterol, or smoke.
Heart disease is more common in people age 65 years or older, especially men. The risk is higher in people of African American, Mexican American, Native American, Native Hawaiian, and Asian American descent.
According to the AHA, major risk factors for heart disease include:
Family history of heart diseaseSmokingHigh cholesterolHigh blood pressureSedentary lifestyleObesity
If you think aspirin therapy may be right for you, be sure to discuss the pros and cons with your doctor. The discussion should take into account your calculated risk for heart disease, the known protective effects of aspirin, potential side effects (such as gastrointestinal bleeding), factors that increase your risk of side effects, and your personal preferences about medical care.
Aspirin and heart disease. American Heart Association website. Available at:
http://www.heart.org/HEARTORG/Conditions/HeartAttack/PreventionTreatmentofHeartAttack/Aspirin-and-Heart-Disease_UCM_321714_Article.jsp. Updated December 11, 2012. Accessed October 6, 2014.
Aspirin for primary prevention of cardiovascular disease. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated March 27, 2014. Accessed October 6, 2014.
Aspirin for the prevention of cardiovascular disease: US Preventive Services Task Force recommendation statement.
Ann Intern Med
. 2009;150(6):396-404. Annals of Internal Medicine website. Available at:
http://www.annals.org/content/150/6/396.full. Accessed October 6, 2014.
Boltri JM, Akerson MR, Vogel RL. Aspirin prophylaxis in patients at low risk for cardiovascular disease: a systematic review of all-cause mortality.
J Fam Pract.
Pearson TA, Blair SN, Daniels SR, et al. AHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update.
Understand your risk of heart attack. American Heart Association website. Available at:
http://www.heart.org/HEARTORG/Conditions/HeartAttack/UnderstandYourRiskofHeartAttack/Understand-Your-Risk-of-Heart-Attack_UCM_002040_Article.jsp. Updated July 16, 2014. Accessed October 6, 2014.
Last reviewed September 2014 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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