Leptospirosis is a rare, but potentially serious, bacterial infection. It is most common in warm, tropical environments, and it spreads easily.
Leptospirosis is caused by specific bacteria resulting from contact with fresh water, wet or dampened soil, or vegetation that has been soiled by urine from an infected animal.
When contact is made with the contaminated material, the bacteria enter the body through open sores or wounds in the skin, or through mucous membranes. When the bacteria has entered the body, it flows into the bloodstream and throughout the body, causing infection.
The following people are at an increased risk of developing leptospirosis: CanoeistsRaftersSwimmers in lakes, rivers, and streamsWorkers in flood plainsWorkers in wet agricultural settingsPeople who have pets, particularly dogs or livestockPeople who work with the land, including farmers, ranchers, loggers, and rice-field workersPeople who work with animals, including veterinarians
Symptoms typically appear about 10 days after infection and may include one or more of the following: Sudden fever, chills, pain, and headacheDry cough
Nausea, vomiting, and
diarrheaAching jointsSore throatPainful bonesAbdominal painRigid musclesRash on the skinYellow skin and eyesReduced urine outputNeck stiffness
You will be asked about your symptoms and medical history. A physical exam will be done.
Your bodily fluids may be tested. This can be done with: Blood testsCultures or other laboratory tests
Talk with your doctor about the best treatment plan for you. Treatment options include antibiotics. In severe cases, hospitalization may be necessary.
To help reduce your chances of getting leptospirosis: Reduce contact with soil, vegetation, and water that could possibly be contaminated with infected animal urine, including urine from rodents.If working with materials that could potentially be contaminated, wear protective clothing that covers the skin, including waterproof boots or waders.If working in an especially high-risk area, talk to your doctor about ways to reduce your risk.
Ellis T, Imrie A, et al. Underrecognition of leptospirosis during
a dengue fever outbreak in Hawaii, 2001-2002.
Vector Borne Zoonotic Dis. 2008;8(4):541-547.
Hartskeerl RA, Collares-Pereira M, et al. Emergence, control and
re-emerging leptospirosis: dynamics of infection in the changing world.
Clin Microbiol Infect.
Katz AR, Buchholz AE, et al. Leptospirosis in Hawaii, USA, 1999-2008.
Emerg Infect Dis.
Leptospirosis. Centers for Disease Control and Prevention website. Available at:
http://www.cdc.gov/leptospirosis. Updated November 18, 2014. Accessed June 11, 2015.
Leptospirosis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated April 3, 2015. Accessed June 11, 2015.
Leptospirosis (Weil's disease). New York State Department of Health website. Available at:
http://www.health.ny.gov/diseases/communicable/leptospirosis/fact_sheet.htm. Updated October 2011. Accessed June 11, 2015.
Stern EJ, Galloway R, et al. Outbreak of leptospirosis
among Adventure Race participants in Florida, 2005.
Clin Infect Dis. 2010;50(6):843-849.
Last reviewed June 2015 by David L. Horn, MD, FACP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © EBSCO Publishing. All rights reserved.