Mucormycosis is an infection that can affect the sinuses, brain, lungs, and sometimes the skin. It is a serious infection that can be fatal.
Mucormycosis is caused by a fungus that is often found in soil, decaying plants or wood, and compost piles. The fungus enters the body through cuts or scrapes in the skin or by being inhaled into the sinuses and airways. Once in the body, the fungus can spread rapidly and quickly become fatal.
A healthy immune system can often manage the fungus and eliminate it before problems begin. However, the fungus can grow and cause severe damage if the body does not have a strong immune system.
A weakened immune system increases your chance of mucormycosis. Conditions or treatments that weaken your immune system include: Diabetic ketoacidosis—a complication of
lymphomaBeing the recipient of an organ transplantLong-term steroid useTreatment with deferoxamine—an antidote to iron poisoningMetabolic acidosis—too much acid in the blood
can also increase your risk of mucormycosis.
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Symptoms will depend on the location of the infection. Inhaled mucormycosis may lead to: FeverFacial painSwollen or protruding eyesRedness of the skin over the sinusesCough; occasionally coughing up bloodShortness of breathAbdominal painVomiting bloodPain in the side between the upper abdomen and the back
An infection in the skin may start with blisters or sores around the skin wound. The skin tissue may later be tender, red, swollen, and turn black.
You will be asked about your symptoms and medical history. A physical exam will be done. A sample of the infected tissue will be taken and examined in a lab.
may be done to look for damage to internal structures.
Mucormycosis is a serious infection and requires aggressive treatment, including surgery to remove dead tissue. Early treatment can lead to better outcomes. Antifungal medication is started as soon as possible. It may be given as a pill or by IV.
The fungus that causes this infection is found in many places. Avoiding contact with it is difficult.
The best preventative step is to control or prevent the conditions that make you vulnerable to mucormycosis.
Mucormycosis. Center for Disease Control and Prevention website. Available at:
Updated February 13, 2014. Accessed June 11, 2015.
Radha S, Tameem T, et al. Gastric zygomycosis (mucormycosis).
The Internet J Pathol. 2007;5(2).
Last reviewed May 2016 by David L. Horn, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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