Stereotactic radiosurgery (SRS) is a way to treat brain disorders. It uses highly focused beams of radiation to target specific areas of the brain. It can also be used on other parts of the body, such as the spine. The beams of radiation destroy the tissue that a neurosurgeon would have removed during an operation.
SRS is used to: Stop cancerous and noncancerous tumor growthShrink cancerous and noncancerous tumors
(AVMs)—abnormal blood vessels that disrupt blood flow to the brain
Treat disorders such as:
Trigeminal neuralgia—a condition that causes facial pain
Epilepsy—a disorder that causes seizures
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Problems from the procedure are rare, but all procedures have some risk. Your doctor will review potential problems, like: HeadacheTemporary swelling at the treatment site, which may be associated with worsening of symptomsSwelling, numbness, bleeding, or tingling around the sites where the head frame rests on the headSkin irritationNauseaSeizuresPatchy hair loss from the radiationPermanent injury to the location in the brain being treated
Rare complications may include: Vision lossDeafnessBleedingNerve problems
Before your procedure, talk to your doctor about ways to manage factors that may increase your risk of complications, such as:
SmokingDrinkingChronic disease such as diabetes or obesity
Other factors that may increase the risk of complications include: Prior surgeriesPrior radiation treatments
You will receive treatment from your doctor and a team of others who specialize in radiation.
Your doctor may do the following: Perform a neurological exam to see how well your nervous system is functioning
MRI scans, or other diagnostic test results
Order additional tests if necessary
Your doctor may ask if you: Take medication or insulin to control diabetesAre allergic to IV contrast material—an injected substance that can make a tumor or other abnormality easier to seeAre allergic to iodine or shellfish—iodine is present in both shellfish and contrast material
or any other medical device implanted in your body
Have eye or ear implantsHave had any previous surgeries
Have ever had
to the skull
Leading up to your procedure: Review your regular medications with your doctor. You may be asked to stop taking some medications before the procedure.
Arrange for someone to:
Drive you to the treatment facilityDrive you home afterStay with you during treatmentStay with you the following nightIf advised by your doctor, use a special shampoo.
The day before your procedure: Do not use any hair creams or hair spray.Do not eat or drink anything after midnight unless told otherwise by your doctor.
The day of your procedure: Bring your regular prescription medications with you to the hospital.Do not wear jewelry, make-up, nail polish, a wig, or a hairpiece.Remove any contact lenses, eyeglasses, or dentures.An IV line will deliver contrast material, medications, and fluids.
You will receive a mild sedative to help you relax.A local anesthetic may be injected to numb your scalp.
There are a few types of SRS:
The procedure will be done using beams of highly focused gamma rays. It is used to treat smaller brain tumors and functional brain disorders.
There are 4 phases to this treatment: Head frame placement—Local anesthesia will be injected into the front and back of your head to numb your scalp. A box-shaped, aluminum frame will be attached to your skull with special pins. This will keep your head from moving during treatment.Imaging—You will have a
to locate the tumor. If you are being treated for an AVM, you may have a test called an angiography to locate the abnormal veins.Computerized dose planning—You will relax for about an hour while your doctors plan your treatment. When they are finished, you will lie down on a special couch. Your doctor will talk to you about the number of treatments you will receive and how long they will take. Your head frame will then be attached to a helmet full of small holes. Each hole will allow a single ray of radiation to target a specific part of your brain.Radiation delivery—The doctors and nurses will leave the room. Your couch will move into the treatment area. You might hear a click as the helmet locks into place. Your doctor will be able to see and hear you during the entire procedure. You will be able to talk to your doctor. You will remain still during the procedure and so will the machinery around you. You will not be able to see, feel, or hear the treatment. When treatment is complete, the couch will move back to its original position.
This treatment uses one large, powerful radiation beam. It is used to treat small and large brain tumors. You will go through the same phases listed above. During radiation delivery, part of the machine will move around you. The treatment couch will also be moved. Some newer systems can also deliver radiation to tumors of the spinal cord.
This treatment is given using a small linear accelerator that is on top of a robotic arm. It is used to treat tumors and injuries of the brain and spine. No head frame is used.
There are 3 phases to this treatment: Set-up—If you are being treated for a brain tumor, a special mask will be made to fit your head. No pins are needed to keep it in place. You will be given a CT scan, and possibly an MRI, with the mask in place.
If you are being treated for a spinal tumor, a customized foam body cradle will be made instead of a mask. You will most likely have some small metal markers called fiducials implanted near the tumor. The markers will help guide the radiation beams during treatment. The fiducials are implanted during a short outpatient procedure. After they are in place, you will be given a CT scan.Treatment planning—You may be allowed to go home while the doctors finalize your treatment plan. Actual treatment may take place that same day or several days after the set-up phase.Treatment delivery—You will be fitted with your mask or body cradle and then lie down on the treatment table. X-rays will be taken before the treatment starts. After treatment begins, the robotic arm will move around you and administer radiation beams from many different angles. Sometimes the arm will stop and more x-rays will be taken.
If your treatment required a head frame: The head frame and IV line will be removed.Your head will be wrapped in gauze or small bandages will be placed at the pin sites.
Radiation delivery can take up to 2 hours for cobalt-60-based treatment and LINAC-based treatments. Robotic radiosurgery treatments can take up to 3 hours.The total procedure usually takes 2-4 hours.
Anesthesia prevents pain at the pin sites if a head frame is used during treatment.You will feel some pressure as the head frame is attached.The treatment itself causes no pain.You may experience headaches or nausea a few hours after treatment. You will be given medication to relieve any discomfort.
During your stay, the hospital staff will take steps to reduce your chance of infection, such as: Washing their handsWearing gloves or masksKeeping your incisions covered
There are also steps you can take to reduce your chances of infection, such as: Washing your hands often and reminding visitors and healthcare providers to do the sameReminding your healthcare providers to wear gloves or masksNot allowing others to touch your incisions
SRS works over time. It may take several months to several years to see results. About one month after your procedure, your doctor will check your pin sites and do a neurological exam.CT scans or MRIs will likely be done sometime after the procedure to determine if treatment was effective. The number of scans and how often you get them may vary.If you were treated for an AVM, you will have a test called a cerebral angiogram 2 to 3 years after treatment. The test will determine if treatment was successful.In many cases, SRS treatments can be repeated, if necessary.
After arriving home, contact your doctor if any of the following occur: Signs of infection, including fever and chillsRedness, swelling, increasing pain, excessive bleeding, or any discharge from the pin sitesPain that you cannot control with the medications you were givenPersistent nausea or vomitingCough, shortness of breath, irregular heart beat, or chest painSevere headacheWeakness, numbness, or loss of balanceVision problemsSeizuresAny new or unexpected
If you think you have an emergency, call for emergency medical services right away.
Frequently asked questions. International Radiosurgical Association website. Available at:
http://www.irsa.org/qa.html. Accessed February 24, 2015.
Linear accelerator. Radiological Society of North America Radiology Info website. Available at:http://www.radiologyinfo.org/en/info.cfm?pg=linac. Updated March 7, 2013. Accessed February 24, 2015.
Radiosurgery. University of Chicago Medical Center website.
http://www.uchospitals.edu/online-library/content=P08476. Accessed February 24, 2015.
Stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Radiological Society of North America Radiology Info website. Available at:
http://www.radiologyinfo.org/en/info.cfm?pg=stereotactic. Updated March 15, 2013. Accessed February 24, 2015.
Last reviewed March 2016 by Mohei Abouzied, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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